How to Put a Dog to Sleep At Home With Benadryl?

Does your dog have a terminal illness that only gets worse as time passes by?

We know how much it hurts to see your beloved pet suffer. When recovery from the illness seems impossible, euthanasia may put them out of their misery. 


What is Dog Euthanasia?

Dog euthanasia is the process of putting your pet to eternal sleep. 

Chronic diseases can lower your pet’s quality of life. Euthanizing them might be more humane than doing treatments with a low chance of recovery.

7 Reasons to Euthanize a Dog

Pet owners may find it hard to euthanize their dogs because of their special bond. Coping with the loss of your dog also isn’t the best feeling in the world. 

Please note: Euthanasia is not for everyone, but here are seven reasons why you might consider putting your pet down. 

1. Your Dog Has An Incurable Disease

If your dog has an incurable disease like cancer, the pain it brings will only get worse. You might consider euthanizing them rather than seeing them suffer every day.  

2. Your Dog Has A Grave Injury

If your dog was involved in a major accident and it incapacitated them to do their usual day-to-day activities, then putting them down is a reasonable thing to do. 

3. Your Dog Can’t Perform Daily Activities

Loss of quality of life is a valid reason to perform euthanasia. If your dog struggles to perform daily activities to the point where they are no longer happy, giving them a peaceful death is worth considering. 

4. Your Dog Is An Elderly One

Elderly dogs often find it hard to enjoy their lives the way they used to. It may be better to euthanize them than to see them unhappy for the rest of their life. 

5. You Cannot Afford Treatment

If your dog suffers from a chronic disease like organ failure, it may need to undergo regular treatment. Medical treatments are expensive and could cost you a lot of bucks. 

Aside from that, the process can deteriorate your dog’s quality of life. In this case, it might be time to say goodbye. 

6. Your Dog Is Aggressive and Dangerous

Was there a time your dog attacked and endangered someone’s life? 

If yes, then you may consider putting your dog down for the sake of others’ well-being and safety. 

When Should You Euthanize Your Dog?

There is no exact time for you to euthanize your dog, but there are signs that may indicate that it’s time to do it. 

1. Your Dog Is In Pain And You Can’t Do Anything About It

Chronic pain from illness or injury can make your dog suffer and decrease its quality of life. 

Before you decide to euthanize your dog, you can consult your vet for pain relief meds. If this method is unsuccessful, there might be no other way to relieve their suffering but to put them to sleep. 

2. Your Dog is Constantly Vomiting 

Incurable and constant vomiting may be an indicator that you euthanize your dog. 

This means that your dog will eventually starve and be dehydrated. Euthanizing them before they experience those harsh conditions might be the better choice. 

3. Your Dog is Disinterested in Everything

Does your dog still get excited whenever they see you? 

How about when you give them their favorite treat? 

Persistent signs of disinterest towards everything show loss in quality of life. Dogs that experience this usually find it hard to feel comfortable. 

If that is the case, it may be time for them to go. Letting them stay when they’re unhappy might make the rest of their life miserable.  

4. Your Vet Says It’s Time

Vets can provide you with sound professional advice on what to do with your dog. 

Before resorting to euthanasia, they would’ve already tried their best to help your dog’s problems. Unfortunately, there are times that euthanasia will be the only option left.  

Is It Legal For Dog Owners To Euthanize Dogs At Home?

Now, you’re probably thinking about euthanizing your dog but are concerned if the process is legal.  We understand where you’re coming from. After all, ending one’s life is usually against the law. 

According to the American Veterinary Medical Association, there are differences in the regulations across the different states. 

In general, euthanasia can only be performed by a licensed vet or a certified euthanasia technician. There are states, however, that allow non-certified people to euthanize their dogs if they are under the direct supervision of a vet. 

Euthanasia laws differ from one state to another, so if you’re unsure whether it’s legal in yours, you can check this document

We suggest you consult your vet before euthanizing your dog at home to make sure you don’t violate any laws. 

5 Reasons Why You Should Consider Euthanizing Your Dog at Home

Here are five reasons to euthanize dogs at home

1. It Is Legal On Your Location

Some states require euthanasia to proceed only in veterinary clinics. So if your state allows performing euthanasia at home, then you should consider it. 

2. You Are On A Tight Budget

Euthanasia procedures in the veterinary clinic can be expensive. If you have the option to euthanize your dog at home, you could cut some costs. 

3. Your Dog Isn’t Comfortable An The Vet Clinic

There is no place more comfortable than your home. Your dog likely feels the same way, too. Euthanizing your dog at the vet clinic might give them unnecessary stress. 

4. You Want To Be Present During Your Dog’s Final Moments

Euthanasia can be a very emotional time for you and your dog. Being there for your dog, both physically and emotionally, can bring them peace. 

This might also help you cope since you get to say goodbye to your buddy. 

5. You Have Contact To A Certified Euthanasia Specialist 

If you know a euthanasia specialist, you may contact them to do the procedure at your home. This would make you feel more secure as you know and trust the person. 

Can You Euthanize Your Dog With Benadryl?

There are a lot of different available options when it comes to euthanasia. Mode of delivery, presence of pain, and cost are some of the things you need to consider when deciding. 

Fortunately, Benadryl is one of the most effective, harmless, and cheap methods to euthanize your dog at home.  

What Is Benadryl?

Benadryl, also known as diphenhydramine, is a common medication for treating people and animals with colds and allergies. 

This medicine is intended for humans, but at the right dosage, it can be perfectly safe for dogs too. 

The Benadryl dosage for dogs should be around 0.9 to 1.8 milligrams (mg) of Benadryl per pound of body weight. Keep in mind that this dosage is for the treatment of allergies, not for euthanizing your dog. 

What Does Benadryl do?

Benadryl is an antihistamine, which means it is used to treat allergies. Within an hour after treatment, symptoms like skin rashes will disappear.  

During long periods of traveling, Benadryl can also bring relief to your dog when they experience motion sickness.

What Are The Effects of Benadryl on Dogs?

With the normal dosage, Benadryl can help your dog in dealing with colds and allergic reactions.

At overdose, the drug will slow down their heart rate and breathing, making them drowsy, until they pass away during their sleep. 

Why Is Benadryl Used For Euthanasia?

Benadryl is a common option for dog euthanasia because of the following reasons:

  • Over-The-Counter Medication
  • Cheap or inexpensive
  • Effective 

In other words, Benadryl is a widely accessible, cheap, and more importantly, effective drug for euthanizing your dog. 

Is It Painful to Euthanize Dogs with Benadryl?

At the correct amount, Benadryl can put your dog down peacefully while they are in deep sleep. 

Too much of an overdose may bring unwanted and uncomfortable side effects, such as: 

  • Seizures
  • Vomiting
  • Diarrhea
  • Rapid breathing

This is why you need to give them the correct dosage so your dog can pass away comfortably. 

Step-By-Step Guide to Euthanizing Your Dog At Home With Benadryl 

Don’t you worry! We are here to show you how to conduct this process properly. So your dog will not experience any problems during the whole procedure.

What You’ll Need

Here are the things you need to euthanize your dog at home with Benadryl:

  • Benadryl
  • Weighing scale 
  • Dog Muzzle
  • Favorite treats of your dog
  • Towels and other cleaning materials

1. Weigh Your Dog

Properly weigh your dog (in kg) using a weighing scale. Euthanizing your dog using Benadryl is dose-sensitive. This means that you need to know their exact weight to calculate the correct dosage.  

2. Determine the Proper Dosage of Benadryl

The proper dosage of Benadryl to euthanize a dog is 24 to 30 mg/kg body weight. For instance, if your dog weighs 20 kg, you need 480 mg to 600 mg of Benadryl to effectively euthanize them. 

If you’re quite unsure whether the dose is correct or you want professional advice, you can always consult your vet. 

3. Restrain Your Dog

The process requires your dog to be in a relaxed position. It should be easy for you to give them Benadryl.

Forcing them to take Benadryl orally might make them agitated. Try to calm them down by giving them their favorite treats. To be sure, you may need to muzzle their mouths. 

4. Administer Benadryl

Once you and your dog are both ready, you can then administer the correct dosage of Benadryl. 

Stay with them for a while. You should notice that their breathing slows down and they get drowsy. They will start falling asleep and eventually go into a coma. 

5. Monitor Them Closely

You need to monitor them for any unwanted side effects like vomiting and diarrhea. Remember that they may twitch and that is normal. 

If their mouth starts to drool or foam, ready your towels and wipe them off. 

6. Take Care of Them

Your dog will pass during sleep. Close their eyes with a towel and handle your dog’s body with extra care. Pay respect for their life and for the happiness they gave you. 

How Long Will It Take For Benadryl To Take Effect And Euthanize Your Dog?

Euthanasia can be a lengthy process. Depending on the weight of your dog, the drug could act faster or later. 

It can take somewhere between 3 to 12 hours after administering Benadryl. You can expect that your dog falls asleep within the first 2 hours. 

Don’t worry if it took longer than you expected. As long as you’ve given them the correct dose, euthanasia should proceed smoothly and successfully. 

What Should You Do After Euthanizing Your Dog?

After your dog passes away, hold them to a proper funeral or burial. Take time to cherish the beautiful memories you’ve had with your dog.  

What Other Medicines Are Used In Dog Euthanasia?

Aside from Benadryl, there are other effective ways to euthanize a dog. 

1. Pentobarbital

Pentobarbital is a seizure medication. In large doses, it can euthanize a dog by shutting down its heart and brain functions. This procedure takes 1-2 minutes. 

2. Tylenol PM

Tylenol PM is also used to euthanize a dog, although it is a very slow process. It could take 24-48 hours before your pet passes away, so it isn’t advised by vets. 

What Are The Other Uses Of Benadryl For Dogs?

Benadryl is not only used for dog euthanasia, here are some of its other uses: 

1. Antihistamine

If your dog has eaten something that caused them to have an allergic reaction, Benadryl can effectively help relieve its symptoms. 

2. Medicine for Motion Sickness

If you’re going on a long trip and you plan to bring your dog with you, the distance may make them feel nauseous. Benadryl can help alleviate motion sickness

10 Ways to Best Cope With Dog Loss

You’ve already spent a lot of time with your dog. Your attachment towards them is so strong that it hurts not to see them again. 

We’re here to help you how to cope with your loss. 

Here are ten ways that may help you go through this difficult time. 

1. Give Yourself Time

Healing takes time. You don’t need to rush yourself to feel better. 

2. Revisit Memories Of Them

Reminiscing about the time you were both happy may help you cope. Don’t forget that you’ve had such a great time together. 

3. Try Not To Blame Yourself For Euthanizing Them

Euthanizing your dog may bring feelings of guilt and anxiety that can haunt you. Remember that it wasn’t your fault and you only did it for their sake. 

4. Hold a Commemorative Event

Sharing their life with others and saying your proper goodbyes will help you move on. Your dog is probably listening to you in doggy heaven! 

5. Process Your Emotions

Allow yourself to grieve about your loss. Cry your heart out if you feel like it. 

6. Find New Hobbies

Doing new things can challenge you and keep your mind off of your loss. Try exercising, swimming, or taking a dance class. 

7. Spend Time With People You Love

When dealing with a loss, it might be a good idea to reconnect with your loved ones. You can invite them over for dinner, watch a movie, or go to your favorite place. 

8. Talk To A Friend

Venting your emotions to a friend you trust can be very comforting. 

9. Talk To a Therapist

If ever you’re finding it hard to cope, you can consult a therapist for professional help. 

10. Get A New Dog

Having a new companion may improve your mood and increase your happiness. It may not be for everyone, but remember that it is an option. 

When to Approach Your Vet About Dog Euthanasia?

If you’re considering euthanizing your dog, then you should approach your vet. They can give you professional advice on how to proceed correctly. 

Even if you’re thinking about putting your pet down at home, you still need to approach your vet before doing it. 


Is It Safe To Give Dogs Benadryl?

Yes. At the proper dosage, it is safe to give dogs Benadryl. It can relieve symptoms of allergies. 

How Much Benadryl Is Safe For Dogs?

The amount of Benadryl that is safe for dogs is around 0.9 to 1.8 mg of Benadryl per lb of body weight. 

How Much Benadryl is Fatal For A Dog?

A dosage of 24 to 30 mg of Benadryl per kg of body weight is fatal for dogs. 

What Is The Best Way To Euthanize A Dog?

The best way to euthanize your dog is the one that you prefer and your vet approves of. 

Is There Any Way to Humanely Euthanize A Dog At Home?

Yes. You can humanely euthanize a dog at home using Benadryl (at the proper dosage).

How Can I Help My Dog Pass Away?

You can help your dog pass away through euthanizing agents such as Benadryl. Before doing it, it is advised that you consult your vet for professional advice. 

Can A Dog Wake Up After Euthanasia?

A dog can wake up after attempting to euthanize them if the procedure isn’t successful. Follow the proper dosage to make sure it goes smoothly. Your dog shouldn’t wake up from the process. 

Do Dogs Know When They Are Dying?

Dogs might have an idea as they near the end of their lives. Some dogs become more clingy, while some can act distant towards you. 

How Much Does It Cost To Put The Dog To Sleep?

Euthanasia can cost differently depending on the method and the location. Putting a dog to sleep starts at $50 for at-home procedures and could go over $400 in a hospital or veterinary clinic. 


The decision to euthanize a dog is never easy to make, but sometimes it’s the one you need to do. 

We understand that your love for your dog tells you to be with them for better or worse. There are times, however, that the best way to express your love for them is to let them go. Letting them experience a peaceful death is better than a slow and painful one. 

Remember that you should consult your vet if you’re considering euthanizing your dog. These professionals can help you make the right decisions.  
Doggos Daily offers you any dog tips and tutorials you’ll need so you can show how much you care for your dog. Want to find out? Visit Doggos Daily now!

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by Nicole Barnett

Nicole has been a freelance writer for over 10 years. She has three dogs, two of which she rescued from the streets. When not furiously typing away at her computer, you’d either find her chasing after her adorable dogs and kids, or volunteering at a local shelter.

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